The DFC offline semi-automated Dissolution testing systems include a dissolution bath, a pump and a fraction collector which will collect the sampled dissolution media. The DSR systems can offer online dilution in addition to the sampling. Automated refilling of the collected media back into the testing vessels is possible for both the DFC and DSR systems.
What Does Semi-Automated Tablet Dissolution Testing Mean?
Semi-automated in this case means automated sampling for a dissolution test instrument at pre-programmed times. Automating this step alone eases the dissolution job a lot. After all samples have been dropped, the dissolution test proceeds automatically and all samples are simultaneously removed from each connected vessel. The sample is delivered into a connected fraction collector by either a PT-SP syringe pump, a peristaltic pump, or a valve-less piston pump. These systems do not require any external PC software to control them (the WinDiss ARGUS dissolution software package can be used optionally). Sampling information is entered directly at the connected Pharma Test dissolution testing instrument.
All tablet dissolution test instruments presented here can be upgraded with a pump and fraction collector, auto sampler or sample processor.
On the left and below you see an overview of the dissolution baths to be upgraded. Please click on the images for more information about performance, accessories, calibration tools and consumables.
DFC systems are composed of a Pharma Test dissolution bath, a PTFC fraction collector and PT-SP syringe pumps
DSR systems are composed of a Pharma Test dissolution bath and a DSR-M dissolution sampling robot with an integrated CAT-M piston pump module
Automated media refilling is possible (Option)
PT-SP High Precision Multi-Syringe Dosing Pump
The PT-SP multi-syringe pump is designed specifically for parallel sample withdrawal and dosage of media from a dissolution bath into open vials inside a fraction collector. It is equipped with up to 8 replaceable 10ml high precision glass syringes. Multiple PT-SP pumps can be connected to each other to operate in a linked mode.
PTFC-2/8 Fraction Collector, for Semi-Automated Tablet Dissolution
The PTFC-2/8 fraction collector can be attached to any Pharma Test dissolution bath and can be used with either PT-SP syringe dosing pumps, peristaltic pumps or valve-less piston pumps. » more information
Systems automate the taking of samples, the most labour intensive stage of a dissolution test
Automated sampling eliminates human errors as equal sampling times and standardized solvent transport offer high reproducability
Offers unattended operation after start of dissolution run