DFC Semi-Automated Tablet Dissolution Testing

The DFC offline semi-automated Dissolution testing systems include a dissolution bath, a pump and a fraction collector which will collect the sampled dissolution media. The DSR systems can offer online dilution in addition to the sampling. Automated refilling of the collected media back into the testing vessels is possible for both the DFC and DSR systems.

What Does Semi-Automated Tablet Dissolution Testing Mean?

Semi-automated in this case means automated sampling for a dissolution test instrument at pre-programmed times. Automating this step alone eases the dissolution job a lot. After all samples have been dropped, the dissolution test proceeds automatically and all samples are simultaneously removed from each connected vessel. The sample is delivered into a connected fraction collector by either a PT-SP syringe pump, a peristaltic pump, or a valve-less piston pump. These systems do not require any external PC software to control them (the WinDiss ARGUS dissolution software package can be used optionally). Sampling information is entered directly at the connected Pharma Test dissolution testing instrument.

All tablet dissolution test instruments presented here can be upgraded with a pump and fraction collector, auto sampler or sample processor.

On the left and below you see an overview of the dissolution baths to be upgraded. Please click on the images for more information about performance, accessories, calibration tools and consumables.

Features

  • DFC systems are composed of a Pharma Test dissolution bath, a PTFC fraction collector and PT-SP syringe pumps
  • DSR systems are composed of a Pharma Test dissolution bath and a DSR-M dissolution sampling robot with an integrated CAT-M piston pump module
  • Automated media refilling is possible (Option)

PT-SP High Precision Multi-Syringe Dosing Pump

The PT-SP multi-syringe pump is designed specifically for parallel sample withdrawal and dosage of media from a dissolution bath into open vials inside a fraction collector. It is equipped with up to 8 replaceable 10ml high precision glass syringes. Multiple PT-SP pumps can be connected to each other to operate in a linked mode.

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DSR-M Auto Sampler, for Semi-Automated Dissolution Testing

The DSR-M automated dissolution sampling robot is designed specifically for the sample transfer and sample processing from a 6 to 8 (DSR-M8) or a 12 to 13 (DSR-M13) vessel dissolution bath.

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DFC-120SP including PTWS 120D Bath, Semi-Automated Dissolution Testing System Composed of:

  • PTWS 120D 6-station dissolution bath with full PTFE tubing installation and resident sampling probes
  • PTFC-2/8SP fraction collector
  • PT-SP6 6-channel high precision syringe dosing pump
  • Optional automated media replacement by an additional PT-SP syringe pump

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DFC-820SP including PTWS 820D Bath, Semi-Automated Dissolution Testing System Composed of:

  • PTWS 820D 8-station dissolution bath with full PTFE tubing installation, EPE-820 auto sampling system and TM-820 tablet drop magazine
  • PTFC-2/8SP fraction collector
  • PT-SP8 8-channel high precision syringe dosing pump
  • Optional automated media replacement by an additional PT-SP syringe pump

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DFC-620SP including PTWS 620 Bath, Semi-Automated Dissolution Testing System Composed of:

  • PTWS 620 8-station dissolution bath with full PTFE tubing installation, EPE automated sampling manifold and TM tablet drop magazine
  • PTFC-2/8SP fraction collector
  • PT-SP8 8-channel high precision syringe dosing pump
  • Optional automated media replacement by an additional PT-SP syringe pump

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DFC-1220SP including PTWS 1220 Bath, Semi-Automated Dissolution Testing System Composed of:

  • PTWS 1220 12-station dissolution bath with full PTFE tubing installation, EPE automated sampling manifold and TM tablet drop magazine
  • PTFC-16SP fraction collector
  • PT-SP8 and a PT-SP6 linked 8 and 6-channel high precision syringe dosing pumps
  • Optional automated media replacement by an additional PT-SP syringe pumps

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DFC-D620SP including PTWS 1220 Bath, Semi-Automated Dissolution Testing System Composed of:

  • PTWS D620 „Dual Drive“ 12-station dissolution bath with full PTFE tubing installation, EPE automated sampling manifold and TM tablet drop magazine
  • PTFC-16SP fraction collector
  • PT-SP8 and a PT-SP6 linked 8 and 6-channel high precision syringe dosing pumps
  • Optional automated media replacement by an additional PT-SP syringe pumps

DFC-70 including PT-DT70 Bath, Semi-Automated Dissolution Testing System Composed of:

  • PT-DT70 7-station dissolution bath with full PTFE tubing installation and resident sampling probes
  • PTFC-2/8 fraction collector (optional E-VEN System for media replacement)
  • 8-channel peristaltic or piston pump (optional 16-channel for media replacement)

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PTFC-2/8 Fraction Collector, for Semi-Automated Tablet Dissolution

The PTFC-2/8 fraction collector can be attached to any Pharma Test dissolution bath and can be used with either PT-SP syringe dosing pumps, peristaltic pumps or valve-less piston pumps.
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